首       頁

技術簡介

產品系列

         薑  黃  素

          白藜蘆醇

          其       他

專利認證

聯繫我們

 

專利

完美的 微活化技術 microActive ®

專利 、高生物利用率、緩釋、安全

   

 

PATENTS

 

U.S. Patent 7,446,101, November 4, 2008 
"Bioavailable carotenoid-cyclodextrin formulations for soft-gels and other encapsulation systems.
"


The present invention describes an improved commercial process for the production of carotenoid-cyclodextrin complexes and formulation of the complex for human ingestion. Complexation with cyclodextrins (e.g., .alpha.-cyclodextrin, .beta.-cyclodextrin, .gamma.-cyclodextrin, or HP-.beta.-cyclodextrin) significantly improves the uptake of carotenoids (e.g., lycopene, lutein, or zeaxanthin) and their mixtures in vitro. The method for making such complexes includes forming a carotenoid/cyclodextrin complex; freezing drying said carotenoid/cyclodextrin complex; and blending said freeze-dried carotenoid/cyclodextrin complex with a mixture of lecithin and a vegetable oil or a vegetable oil suitable for soft gelatin capsules. The cyclodextrin/carotenoid complex can be formed in a molar ratio of between about 0.5:1.0 and 10:1. In vivo, in a human study, the lutein/.gamma.-cyclodextrin complex formulated in lecithin-oil or oil showed a better absorption of lutein, as compared to the free lutein-oil formulation.

 

U.S. Patent 7,297,803, November 20, 2007
"Process for the preparation of lutein esters."

 

A method for concentrating trans-lutein esters from marigold oleoresin, which includes blending the oleoresin with a solvent and a co-solvent of lower alkanols and recovering a precipitate enriched with trans-lutein esters at a temperature of above 22.degree. C. The recovery of the trans-lutein esters is greater using the alkanol blend than when using only a lower alkanol in the said blend. The process is most useful using a lower-grade, commercially available oleoresin, thereby helping small producers, who do not have access to higher-grade oleoresin made through backward integration to marigold cultivation and harvest.

 

U.S. Patent 7,030,102, April 18, 2006
"Highly bioavailable coenzyme Q-10 cyclodextrin complex."

 

The present invention is based on the unexpected discovery that CoQ-10 can be made commercially in a highly bioavailable form suitable for topical, sublingual formulations, or for oral ingestion. complex. Complexation in general with .gamma.- or .alpha.-cyclodextrin improved the cellular uptake of CoQ-10 as compared to water dispersible liposomal or micellar forms of CoQ-10. Thus, the present invention includes a highly bioavailable CoQ-10/cyclodextrin complex for use in the nutritional supplement, oral care, and pharmaceutical industry.

 

U.S. Patent No. 6,380,442, April 30, 2002
"Process for the isolation of mixed carotenoids from plants."

 

A practical and effective process for isolating and purifying mixed carotenoids containing higher concentrations of specific compounds, such as all-trans lutein, without the use of harmful organic solvents, is disclosed. The process employs hydrolysis of carotenoid esters in a mixture of isopropanol, water, and alkali to separate the carotenoids from other impurities. The carotenoids are purified further using aqueous precipitation, followed by centrifugation and drying under vacuum. The product is a fine crystalline powder with very low residual solvents (hexane 0.22 ppm; isopropanol 0.53 ppm) suitable for human consumption, either in nutritional supplements or as a food additive.

 

US Patent No. 6,254,898 (For a BioActives client)
"Nutraceutical Composition for Protection Against Solar Radiation"

 

The company conducted the research, wrote and filed the patent for its client Protective Factors.

 

PATENTS PENDING

 

"Water-dispersible policosanol cyclodextrin complex and method of its production"

 

"Oral-care formulations comprising highly-bioavailable Coenzyme Q10 cyclodextrin complex"

 

 
 

本網頁版權所有,未獲授權,請勿複製、擷取、引用。

本網頁所有資料未經衛生署或FDA證實,不能作為任何醫療診斷、治療、預防疾病...等用途, 亦不得引用做為任何商業用途,僅提供做為學術及研究參考之用

註冊商標未獲授權切勿擅用。

 

B